Controlled trial of imipramine in diurnal enuresis.
نویسندگان
چکیده
Twenty-seven children with diurnal enuresis were studied in a double-blind randomised controlled trial of imipramine. Outcome was not related to such features as age, gender, maximum functional bladder capacity, or evidence of psychiatric disturbance. Although the condition in several children improved, no evidence emerged to suggest that imipramine was superior to placebo in the treatment of the condition.
منابع مشابه
Combined Treatment with Oxybutynin and Imipramine in Enuresis
Background: Primary nocturnal enuresis is a common disorder that often leads to considerable distress in affected children and their family. In many countries pharmacologic therapy is preferred to non-pharmacologic behavioral and conditional alarm therapy. Imipramine, oxybutynin, and desmopressin have been used for enuresis with various efficacies. The aim of the present study was to compare th...
متن کاملSuccessful management of daytime enuresis using alarm procedures: a randomly controlled trial.
Forty four children with daytime wetting were included in a randomly controlled trial of two alarm devices, a contingent one that sounded when wetting occurred and a non-contingent one that went off from time to time unrelated to wetting events. A quota allocation system ensured comparability between treatment groups. Two thirds responded to an alarm by becoming dry. The non-contingent alarm pr...
متن کاملDesmopressin, Imipramine, and Oxybutynin in the Treatment of Primary Nocturnal Enuresis: A Randomized Clinical Trial
BACKGROUND Nocturnal enuresis is the most common pediatric urologic problem in outpatient clinics. OBJECTIVES To assess the effect of various monotherapies, and comparing the effects of desmopressin, imipramine, and oxybutynin in children with enuresis, as well as the influence of socioeconomic and cultural factors of their families on the response and relapse rates. PATIENTS AND METHODS Th...
متن کاملNocturnal enuresis: a placebo controlled trial of two antidepressant drugs.
A multicentre, randomised, double blind treatment trial was set up comparing imipramine (a tricyclic antidepressant with anticholinergic action), mianserin (a quadricyclic antidepressant without anticholinergic activity), and placebo, (a) possibly to identify an effective alternative drug and (b) to elucidate the action of imipramine in enuretic children. Eighty children (65 boys, 15 girls) age...
متن کاملDrugs for nocturnal enuresis in children (other than desmopressin and tricyclics).
BACKGROUND Enuresis (bedwetting) is a socially unacceptable and stressful condition which affects around 15-20% of five year olds, and up to 2% of young adults. Although there is a high rate of spontaneous remission, the social, emotional and psychological costs to the children can be great. OBJECTIVES To assess the effects of drugs other than desmopressin and tricyclics on nocturnal enuresis...
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ورودعنوان ژورنال:
- Archives of disease in childhood
دوره 57 9 شماره
صفحات -
تاریخ انتشار 1982